http://docs.info.apple.com/article.html?artnum=305042 Apple has released a new version of iTunes that addresses a number of compatibility issues with Windows Vista. iTunes 7.1.1 is recommended for use with most editions of Windows Vista, however, Apple is actively working with Microsoft to resolve a few remaining known issues. This document will be updated as more information becomes available.
If you are upgrading to Windows Vista or have purchased a new computer with Windows Vista pre-installed, here is some information you may find helpful:
I have a new computer with Vista. I have itunes 7.1.1 and I haven't had any problems. I have music, audiobooks and pictures and so far everything works OK. Now that I have said that the whole thing will probably crash.