My MIL has a beautiful calico that has been spayed and de-clawed. She was a really sweet kitten but has grown into a hateful biting, headstrong feline. She will bite and doesn't draw blood but has already (keep in mind she is almost 2 yo) my MIL as she walks through the house, when she is sitting on the couch reading she attacks her hands, and she doesn't ever want to be petted, she'll grab your hand and bite, she growls when you just look at her, I have to admit I'm not a cat person and this cat has reenforced that. They have tried everything from squirting her with water when she gets up on the table, flipping her nose when she bites, and she will just look at them and continue what she is doing. They have tried ignoring her, much to her delight and they are really getting fed up. My FIL has a little better luck with her but only marginally, and she treats everyone who enters the house with the same nasty attitude. Any suggestions? I think my MIL is getting fed up and to be perfectly honest, I don't blame her. She has been to the vet for a complete check up so there is nothing medically wrong with her. The vet says that calico's tend to have a sassy, less friendly attitude. To me that's like saying all red headed people have a short temper. Can any one offer any suggestions as to what they can do?