hyperthyrriod/valleyfever combo
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Thread: hyperthyrriod/valleyfever combo

  1. #1
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    Defaulthyperthyrriod/valleyfever combo

    I have a three yr old yellow lab, diagnosed with valley fever at 1/1/2yrs, hyperthyroidism at 2 yrs.
    Health is very good, activity level a little below normal, but otherwise healthy, weight ok.
    1 yr on 400 mg of fluconazole, twice daily, and titer levels have not dropped at all, 1 yr on Soloxine 1.2 mg twice daily.
    The thyroid levels have not changed at all, and now titer levels for valley fever have gone up again.
    My vet accuses us of not giving the dog her medication, he is VERY wrong with that assumption!
    I have asked if there is a malabsortion problem with the medication, but the vet says after 27 yrs in the biz, he's never seen anything like this.
    Just wondering if anyone has any input to share with this problem!!!

    Thanks

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  3. #2
    CaliforniaLabLover's Avatar
    CaliforniaLabLover is offline Senior Member
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    DefaultRe: hyperthyrriod/valleyfever combo

    Sounds like you have hypothyroidism (vs. hyperthyroidism, which is rare in dogs and usually a result of a tumor) going on, since you have to supplement with soloxine. Pretty common, especially when going through bouts of any chronic illness.

    There are a lot of antifungal drugs out there...if this one isn't cutting it, and your vet doesn't have any suggestions, I would personally go see an internal medicine specialist, and make sure going in that they know that your dog is being treated for valley fever without much improvement. I'm sorry to hear about this. Poor girl.

    ~Julie, Rogue, Monty, and Eddy~

    "The reason a dog has so many friends is that he wags his tail instead of his tongue." -Anon

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    dogmom is offline Senior Member
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    DefaultRe: hyperthyrriod/valleyfever combo

    From where are you purchasing the fluconazole? How much does the dog weigh? And are there any other medications you are giving, any homeopathics?

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  6. #4
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    DefaultRe: hyperthyrriod/valleyfever combo

    An expert from Arizona's premier VF research center, Valley Fever Center for Excellence http://www.vfce.arizona.edu/VFID-home.htm, just spoke here in Phoenix.* I was not able to attend but several of my training buddies and Essy's breeder attended.* They all have dogs with VF and one also has a dog with a thyroid problem. Anyway, I'd be happy to put you in touch with them.* They would be able to share the info with you.* Specifically I remember them saying that it is normal for the titers to go up after a period of time.* The dr also gave info about the drugs used to treat VF and the best places to purchase them in AZ.* Just let me know if you want the contact info.


  7. #5
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    DefaultRe: hyperthyrriod/valleyfever combo

    Thanks to everyone for the input!
    I would appreciate the contact information for the Valley Fever place, it seems to be a very misunderstood illness (it took an emergency clinic 4 days to finally test for it)!
    The Fluconazole was coming from a vet pharmacy, and we have now changed to Diamondback Drugs, for the source, but still no change! The pills are compounded due to the high dosage required.
    Riley's about 96 pounds. Shes in good shape, big boned, but not fat at all. (well, a little heavy in the chest!) But otherwise healthy!
    The vet has recommended against any homeopatic supplements, anybod's input on that would also be helpful!

  8. #6
    Labs4me is offline Senior Member
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    DefaultRe: hyperthyrriod/valleyfever combo

    Where are you located? Has this dog ever been checked for tick born illness especially Lymes? Given that your dog has been on meds for a number of years the tests can come back with a false negative for Lymes. I have a old girl here that for 2 years never tested pos for Lymes. I finally found a place that can do Lymes testing even if the dog has been on antibiotics, ect and low and behold it came back positive. I am not happy that she has Lymes but I am happy to finally have some proof that it is indeed Lymes we are dealing with. Contact Bowen research at 863-956-3538. They will also send you out a kit for collection to take to your vet. They can send the kit to your home and you can take it to your own vet, OR you can have the vet contact them and they will ship it directly. There is no charge for the kit. We do ask for a donation of $150.00 to run the testing on animal blood. We are a non profit organization and contributions to us are tax deductible.

    Also do a search on google for Susan Netboy lymes (both together and seperate) and you will come up with several great resources on tick illnesses.
    Bonnie ~ Ellsworth Labradors
    Home to Ellsworth's Playing For Keeps CGC, U-CH SHR Ellsorth's Absolut Pleasure, Ellsworth's Good Luck Charm
    Gone but not forgotten: Franklin's Lucy of Ellsworth; Franklin's Rare Treat; U-CD Franklin's Rockin' Robin CDX, WC, CGC; Alpha-Omega's Mustang Salli CDX, CGC

  9. #7
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    DefaultRe: hyperthyrriod/valleyfever combo

    We are in Phoenix, no tick problems, and tested negative for Lyme, and Tick fever, but was recently vaccinated for Lyme, and other stuff, since we will be moving to Missouri in the next couple of months.
    Vet said incidence of side effects are virtually nill...but who knows. Could be playing with her immune system?

  10. #8
    Labs4me is offline Senior Member
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    DefaultRe: hyperthyrriod/valleyfever combo

    When was the dog tested for Lymes and what type of a test was used (ie Western Blot or IFA)? At the time of testing was the dog on or had it been on any medications and if so what were they? Also where was the test done?

    How long ago was the dog vaccinated for Lymes? They have had problems with the vaccine causing lymes and lymes symptoms, I don't care if the vet said the side effects were virtually nill. After having a dog with lymes and seeing what it does to them I would never give this vaccine. By the way the human version on the Lymes vaccine was pulled off the market a number of years ago due to problems croping up. Once you have Lymes you have it for life you can't kill the organizm and it can affect any number of systems in the body (nervous system, cardiac, enlarged heart, ect.). Lymes is called the great intimidator for a reason, a great number of people have been misdiagnoised for years with things like MS, ALS, Ahlzhiemer's, lupus, ect before finally learning that they have Lymes instead.

    Also found this web site on valley fever:
    http://www.thepetcenter.com/gen/fungal.html
    http://www.goldacregoldens.com/valleyfvr.html
    One on tick illness:
    http://web.archive.org/web/200306211...ehrlichia.html
    Bonnie ~ Ellsworth Labradors
    Home to Ellsworth's Playing For Keeps CGC, U-CH SHR Ellsorth's Absolut Pleasure, Ellsworth's Good Luck Charm
    Gone but not forgotten: Franklin's Lucy of Ellsworth; Franklin's Rare Treat; U-CD Franklin's Rockin' Robin CDX, WC, CGC; Alpha-Omega's Mustang Salli CDX, CGC

  11. #9
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    DefaultRe: hyperthyrriod/valleyfever combo

    Riley was tested about 2 mons ago, don't know which test was done, but vet said needed to test negative before the vaccine. She got the vaccine about 1 1/2 months ago. The test was done at the regular lab which he uses, (don't know the name?!?!)
    Vet said even Lyme wouldn't effect her thyroid like this, of course I'm not a doctor, so what the heck do I know?
    At the time of testing she was on Flconozole, for VF, and her regular Soloxine.

  12. #10
    dogmom is offline Senior Member
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    DefaultRe: hyperthyrriod/valleyfever combo

    At the previous clinic I worked at, we participated in the U of A Valley Fever Center for Excellence initial study program. We had more than 25 clients involved, attended monthly evaluations of the pets (several were cats), compiled more data then you can imagine and had the privilege to work closely with Dr. Lisa Schubetz.

    As Lydia said, it is not unusual for the titer to increase during the treatment. If it is in the bone and or brain , it is common for it to elevate before coming down. HOWEVER, it is also common that if the Cocci is in the bone/brain, the pet may be on fluconazole forever (My sons dog has it in the pelvis and has been on fluconazole for 5 years). Dogs with metabolic disease have shown to be slightly more resistant to treatment but generally respond. It is also recommended to give Vit.C with the fluconazole to assist with absorption.

    Fluconazole is the gold standard in treatment but the medication can be "better" at some pharmacies. Compounding can cause the mg to be inexact, so it may not be 400mg. but 350mg. That can make a big difference in how a pet responds. Efficacy testing did show that Pet Health Pharmacy fluconazole was exact, as well as Roadrunner Pharmacy. Both are in the Phoenix area but will also mail meds.

    Also was the thyroid testing done by Michigan State? If not, I would request it be redone and sent there. Michigan is also the "gold standard" for thyroid testing.

    How is your dog acting? Do you see an improvement since the initial diagnosis?

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