LEPTOSPIRA VACCINE--Adverse Reactions
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    DefaultLEPTOSPIRA VACCINE--Adverse Reactions

    LEPTOSPIRA VACCINE--Adverse Reactions

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    Regarding the Lepto vaccine, on Page 2 of the American Animal Hospital Association's 2003 Canine Vaccine Guidelines and Recommendations, it states that "Optional or 'noncore' vaccines are those that the committee believe should be considered only in special circumstances because their use is more dependent on the exposure risk of the individual animal. Issues of geographic distribution and lifestyle should be considered before administering these vaccines. In addition, the diseases involved are generally self-limiting or respond readily to treatment. The committee believes this group of vaccines comprises distemper-meases virus (D-MV), canine parainfluenza virus (CPIV), Leptospira spp., Bordetella bronchispetica, and Borrelia burdorferi."

    Furthermore, on Page 7, Tables 1 of the AAHA Guidelines referenced above, it states under Revaccination (Booster Recommendations) that the Leptospira interrogans vaccine "....this product carries high-risk for adverse vaccine events." Under Overall Comments and Recommendations they elaborate: "Anecdotal reports from veterinarians and breeders suggest that the incidence of postvaccination reactions (acute anaphylaxis) in puppies (<12 wks of age) and small-breed dogs is high. Reactions are most severe in young (<9 wks of age) puppies. Routine use of the vaccine should be delayed until dogs are >9 wks of age."

    On Page 8 of the 2006 American Animal Hospital Association's Canine Vaccine Guidelines, it states that "Veterinarians are advised of anecdotal reports of ACUTE ANAPHYLAXIS in TOY BREEDS following administration of leptospirosis vaccines. Routine vaccination of toy breeds should only be considered in dogs known to have a high exposure risk."

    Leptospira is a “killed” vaccine and is associated with clinically significant adverse reactions. According to the 2003 AAHA Guidelines (Page 16), "...killed vaccines are much more likely to cause hypersensitivity reactions (e.g., immune-mediated disease)." Further, the AAHA task force reports on Page 18 that, "Bacterial vaccines, especially killed whole organism products …..are much more likely to cause adverse reactions than subunit or live bacterial vaccines or MLV vaccines, especially if given topically. Several killed bacterial products are used as immunomodulators/adjuvants. Thus, their presence in a combination vaccine product may enhance or suppress the immune response or may cause an undesired response (e.g., IgE hypersensitivity or a class of antibody that is not protective)."

    The Leptospira vaccine is also an "adjuvanted" vaccine, as are the Lyme and Rabies vaccines. "The World Health Organization (WHO) in 1999 classified veterinary vaccine adjuvants as Class III/IV carcinogens with Class IV being the highest risk," IARC Monographs on the Evaluation of Carinogenic Risks to Humans: Volune 74, World Health Organization, International Agency for Research on Cancer, Feb. 23-Mar. 2, 1999, p. 24, 305, 310.

    A fuller discussion of the Lepto vaccine can be found on Page 14, in which it is reported that, "Immunity is an ill-defined term for Leptospira ssp. products. If immunity is defined as protection from infection or prevention of bacterial-shedding, then there is little or no enduring immunity."

    Dr. Alice Wolf, Professor of Small Animal Internal Medicine at Texas A&M College of Veterinary Medicine, stated in an address (Vaccines of the Present and Future http://www.vin.com/VINDBPub/SearchPB...00/PR00141.htm) at the 2001 World Small Animal Veterinary Association World Congress that: "The most reactive vaccines for dogs include leptospirosis bacterin and Borrelia [Lyme]vaccine.".

    Personally, I found the most stunning quote in this entire document to be on Page 18, in which the task force declares: "However, the ethical issue that our profession struggles with today is whether economics justifies giving an animal a drug (vaccines are biologic drugs) that is not necessarily required. As a minimum, we should allow pet owners to make this choice rather than make it for them."

    Combination Vaccines, Multiple Shots--on Page 16 of the 2003 AAHA Guidelines under Immunological Factors Determining Vaccine Safety, it states that: "Although increasing the number of components in a vaccine may be more convenient for the practitioner or owner, the likelihood for adverse effects may increase. Also, interference can occur among the components. Care must be taken not to administer a product containing too many vaccines simultaneously if adverse events are to be avoided and optimal immune responses are sought. "
    __________________________________________________ _________________
    Duration of Immunity: The Rabies Vaccine Challenge - Show #185 Animal Talk Radio Show 7/30/08 http://www.blogtalkradio.com/animalt...lenge-Show-186

    Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz http://www.cedarbayvet.com/duration_of_immunity.htm

    What Everyone Needs to Know about Canine Vaccines, Dr. Ronald Schultz
    http://www.puliclub.org/CHF/AKC2007C...20Vaccines.htm

    Vaccination: An Overview Dr. Melissa Kennedy, DVM360 http://veterinarycalendar.dvm360.com....jsp?id=568351

    World Small Animal Veterinary Association 2007 Vaccine Guidelines http://www.wsava.org/SAC.htm Scroll down to Vaccine Guidelines 2007 (PDF)

    The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at http://www.leerburg.com/special_report.htm .

    The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at http://www.aahanet.org/PublicDocumen...s06Revised.pdf .

    Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at http://www.newvaccinationprotocols.com/

    October 1, 2002 DVM Newsletter article entitled, AVMA, AAHA to Release Vaccine Positions, http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=35171

    July 1, 2003 DVM Newsletter article entitled, What Do We Tell Our Clients?, Developing thorough plan to educate staff on changing vaccine protocols essential for maintaining solid relationships with clients and ensuring quality care http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61696

    July 1, 2003, DVM Newsletter article, Developing Common Sense Strategies for Fiscal Responsibility: Using an interactive template to plan service protocol changes http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61694

    Animal Wellness Magazine Article Vol. 8 Issue 6, How Often Does he REALLY Need A Rabies Shot Animal Wellness Magazine - devoted to natural health in animals

    The Rabies Challenge Animal Wise Radio Interview
    Listen to Animal Wise (scroll down to The Rabies Challenge 12/9/07)

    The Vaccine Challenge Animal Talk Naturally Online Radio Show » The Vaccine Challenge - Show #91

    Rabies Shot Killed my Poodle May 28, 2008 Channel 5 News WCVB http://www.thebostonchannel.com:80/n...ss=bos&taf=bos

    US Declared Canine-Rabies Free -- CDC Announces at Inaugural World Rabies Day Symposium CDC Press Release - September 7, 2007

    Rabies Prevention -- United States, 1991 Recommendations of the Immunization Practices Advisory Committee (ACIP), Center for Disease Control's Morbidity and Mortality Weekly March 22, 1991 / 40(RR03);1-19 http://www.cdc.gov/mmwr/preview/mmwrhtml/00041987.htm "A fully vaccinated dog or cat is unlikely to become infected with rabies, although rare cases have been reported (48). In a nationwide study of rabies among dogs and cats in 1988, only one dog and two cats that were vaccinated contracted rabies (49). All three of these animals had received only single doses of vaccine; no documented vaccine failures occurred among dogs or cats that had received two vaccinations. "
    Kris L. Christine
    Founder, Co-Trustee
    The Rabies Challenge Fund
    www.RabiesChallengeFund.org

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    I'm totally with you on the vaccination thing. I'm just wondering why you're getting so much negative feedback? I'm kinda surprised at some of the comments in the other thread.

    On the lepto vaccine, I believe it is a terrible choice to vaccinate for lepto! It is mostly self limiting and a self limiting disease or infection should not be vaccinated against.

    Taken from the wing-n-wave website http://www.labbies.com/lepto.htm

    Prognosis. Fatalities as a direct result of Leptospirosis do not usually exceed 10% and usually occur 5-10 days after initial onset of the disease. Death arising from secondary complications associated with progressive kidney and liver damage are common but may not occur for long periods following the initial disease.

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    Captaincool,

    A great deal of money is made on vaccinations, and there are those who would prefer I not share information. Perhaps the quotes and links below to articles from veterinary trade publications will give you some insight.

    Kris

    Veterinary trade publications have frankly addressed the issue of the link between vaccines and income.

    A related story Improving Veterinarians' Income a Top Goal of AVMA President-elect candidate Childers. can be found at http://www.avma.org/onlnews/javma/mar04/040315g.asp.

    In an August 2004 cover story in Veterinary Economics entitled Targeting Changing Vaccine Protocols by Roger F. Cummings, they state that: "In the 1970s and ’80s many veterinarians derived a substantial percent of their total incomes from vaccinating dogs and cats. .....And in many practices today, the vaccination reminder is the one thing that drives visits from healthy pets. So changing your vaccine protocols could have a significant affect on practice finances."

    Dr. Alice Wolf, Professor of Small Animal Internal Medicine at Texas A&M College of Veterinary Medicine, stated in an address (Vaccines of the Present and Future http://www.vin.com/VINDBPub/SearchPB...00/PR00141.htm) at the 2001 World Small Animal Veterinary Association World Congress that: “some veterinarians use the recommendation for vaccinations as a way to ensure client visits for yearly examinations and, least appropriate, as a ‘profit center.’”

    In an October 1, 2002 DVM Newsletter article entitled, AVMA, AAHA to Release Vaccine Positions, http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=35171, Jennifer Fiala reports, "The statement stresses AVMA's stance on education, a reduction in the profession's dependence on vaccine sales, which account for a significant portion of practice income, ..........Veterinarians must promote the value of the exam and move away from their dependence on vaccine income. "

    DVM's July 1, 2003 article, Developing Common Sense Strategies for Fiscal Responsibility http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61694 declares that, "The purpose of this article is to focus on the third of these essential cornerstones: the economic realities of protocol changes, and how medical and surgical standards including reduced frequency of vaccination can be compatible with financial viability; and, yes, even success. ........For a real eye-opener of potential revenue loss, research practice records for the most recent 12 months of client activity to determine the estimated number of adult canine patients that were seen for annual vaccinations. Multiply this number times the revenue loss calculated above on an individual patient basis to determine the total potential lost income. "

    From a July 1, 2003 DVM article entitled, What Do We Tell Our Clients? , http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61696, "It has finally happened. The American Animal Hospital Association (AAHA) has released canine vaccine guidelines. Some practitioners may dread it and consider the recommendations as a 'practice buster.' ......The concern of course is the loss of our 'vaccine hook.' "

    On Page 18 of the American Animal Hospital Association's 2003 Canine Vaccine Guidelines, http://www.leerburg.com/special_report.htm the task force declares: "However, the ethical issue that our profession struggles with today is whether economics justifies giving an animal a drug (vaccines are biologic drugs) that is not necessarily required. As a minimum, we should allow pet owners to make this choice rather than make it for them."


    October 1, 2002 DVM Newsletter article entitled, AVMA, AAHA to Release Vaccine Positions, http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=35171

    July 1, 2003 DVM Newsletter article entitled, What Do We Tell Our Clients?, Developing thorough plan to educate staff on changing vaccine protocols essential for maintaining solid relationships with clients and ensuring quality care http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61696

    July 1, 2003, DVM Newsletter article, Developing Common Sense Strategies for Fiscal Responsibility: Using an interactive template to plan service protocol changes http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61694
    Kris L. Christine
    Founder, Co-Trustee
    The Rabies Challenge Fund
    www.RabiesChallengeFund.org

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    Quote Originally Posted by Kris L. Christine View Post
    Captaincool,

    A great deal of money is made on vaccinations, and there are those who would prefer I not share information. Perhaps the quotes and links below to articles from veterinary trade publications will give you some insight.

    Kris
    UGH. Kris, it's not that anyone is trying to silence you - it's that you cut and paste quotes together from scientific articles using ellipses to make whatever point you want - with complete disregard for the actual point, purpose, or topic of the article.

    Yes, when the 3-year vaccine came out there was concern about how vets would continue to make money - A VALID CONCERN. If your business suddenly was faced with a loss of thousands of dollars of revenue per year would you not be trying to think of ways to recover it? Would you not be discussing said revenue loss? There was discussion about which was the best way to recover lost revenue. Not ONE article you posted recommended ignoring or not following the 3-year vaccination protocol. So what is your point?

    That vets make money on vaccines? Sure do. No one denies that. They also make money on well-pet visits - should we stop those? They make money on heartworm treatment - should we stop that? They make money on fecals - should we stop doing those? Perhaps we should stop paying vets all together, and just let them do their work out of the kindness of their hearts. Then we could be sure they aren't all plotting ways to kill our pets right?

    My issue with your posts is they are MISLEADING and devoid of any actual use. You do not participate in the forums except to spam them with ANNOYING CAPITAL LETTER THREAD SUBJECTS. It's like if I took your quote above and did what you do with the articles you post, I could get this:

    "A great deal of money is made on ... shar[ing] information." Kris L. Christine
    Thus implying that you get paid per post by some organization, which, I don't *think* that you do.

    Only after the last tree has been cut down, only after the last river has been poisoned, only after the last fish has been caught, only then will you find that money cannot be eaten. - Cree prophecy

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    Quote Originally Posted by YellowJakesMom View Post
    UGH. Kris, it's not that anyone is trying to silence you - it's that you cut and paste quotes together from scientific articles using ellipses to make whatever point you want - with complete disregard for the actual point, purpose, or topic of the article.

    Yes, when the 3-year vaccine came out there was concern about how vets would continue to make money - A VALID CONCERN. If your business suddenly was faced with a loss of thousands of dollars of revenue per year would you not be trying to think of ways to recover it? Would you not be discussing said revenue loss? There was discussion about which was the best way to recover lost revenue. Not ONE article you posted recommended ignoring or not following the 3-year vaccination protocol. So what is your point?

    That vets make money on vaccines? Sure do. No one denies that. They also make money on well-pet visits - should we stop those? They make money on heartworm treatment - should we stop that? They make money on fecals - should we stop doing those? Perhaps we should stop paying vets all together, and just let them do their work out of the kindness of their hearts. Then we could be sure they aren't all plotting ways to kill our pets right?

    My issue with your posts is they are MISLEADING and devoid of any actual use. You do not participate in the forums except to spam them with ANNOYING CAPITAL LETTER THREAD SUBJECTS. It's like if I took your quote above and did what you do with the articles you post, I could get this:



    Thus implying that you get paid per post by some organization, which, I don't *think* that you do.
    Ah I see now, and I was completely sucked into the hype. Not that I disagree with a lot of the stuff, but you're right in the way you make the point. My apologies.

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    Quote Originally Posted by YellowJakesMom View Post
    My issue with your posts is they are MISLEADING and devoid of any actual use. Thus implying that you get paid per post by some organization, which, I don't *think* that you do.
    Giving dog owners access (through links) to information on canine vaccines from authoritative sources like the American Animal Hospital Association, the Center for Disease Control's Association of State Public Health Veterinarians and the World Small Veterinary Association, etc... may be of no use to you, but there are many, many dog owners whose veterinarians fail to give them full disclosure about the known minimum duration of immunity of the canine vaccines they annually inoculate their animals with, and some of them find the information helpful.

    Dog owners have the right to access information to better educate themselves on canine vaccines, and I am happy to provide links for them to read the complete articles,reports, and studies which I post quotes from. Giving dog owners on this forum credit, I am sure they are capable of reading the 2003 AAHA Canine Vaccine Guidelines and determining whether they want to vaccinate their animals against distemper annually, triennially, or do titers instead.

    It costs me a great deal of money to do what I do, and I provided the seed money to start The Rabies Challenge Fund -- not I or anyone associated with the RCF are paid or reimbursed for expenses, everyone associated therewith is a volunteer who shoulders the costs of their activities.
    Kris L. Christine
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    www.RabiesChallengeFund.org

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    I think you missed the point of my post.

    I have no issue with dog owners' access to information. It would be great if more people knew about titers and the AAHA vaccine protocol. I helped raise money to donate to RCF. No one is trying to stop the education of dog owners, just the *mis*education.

    My problem is that a number of your posts imply things that the articles simply do not state. Specifically, your recent post that seemed to imply AAHA was in support of not vaccinating puppies until they were 16 weeks.

    You know that's not true. I know that's not true. But how many people do you really think read the full links you post and not just the selected bits you choose to highlight? I would guess the majority don't - they take your word for it. Which in that case, was dead wrong (literally, dead in the case of some people choosing not to vaccinate puppies until 16 weeks and then doing hairbrained things like taking them to dog parks).

    I'm happy there is a Rabies Challenge Fund, I'm glad there's been work to establish at least a 3 year efficacy for core vaccines, but I take issue with your essential spamming of internet message boards with sometimes false or misleading information. IMO, there are better and more accurate, truthful ways to spread the word about making an *informed* choice about vaccinating one's dogs.

    Only after the last tree has been cut down, only after the last river has been poisoned, only after the last fish has been caught, only then will you find that money cannot be eaten. - Cree prophecy

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    YellowJakesMom,

    It would be helpful if you would post some links to information so lab owners on this forum can do some research on canine vaccines, do you have any you could share?
    Kris L. Christine
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    I'm not sure what point you're trying to make Kris.

    I've told you I agree with the basic premise of your posts (overvaccination = bad), but disagree with your presentation methods in some posts.

    If someone asks about titers, 3 year protocols, or things like that, and other people haven't yet replied, I'm happy to share my opinions or information I've found (AAHA vaccine protocols, Dr. Littman's report on Lyme Vaccinations and adverse effects in labs for ACVIM, etc.). However, I generally don't post random links or collections of links, I choose to participate in threads and the forum instead.

    You go right ahead and do what works for you though - again, I'm not saying don't post. Just don't expect me to be silent if you imply AAHA advocates waiting until 16 weeks to vaccinate puppies.
    Last edited by YellowJakesMom; 03-28-2009 at 03:36 PM.

    Only after the last tree has been cut down, only after the last river has been poisoned, only after the last fish has been caught, only then will you find that money cannot be eaten. - Cree prophecy

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